Is predicted to encode a protein with the following domains: Cullin protein, neddylation domain; Winged helix DNA-binding domain superfamily; Winged helix-like DNA-binding domain superfamily; Cullin protein neddylation domain; and Cullin homology domain superfamily. Is an ortholog of C. elegans
cul-1 and
cul-6. In C. elegans,
cul-1 is involved in several processes, including determination of adult lifespan; negative regulation of cell cycle; and regulation of apoptotic process.