gene: cog-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor binding activity. Involved in several processes, including determination of left/right symmetry; neuron development involved in amphid sensory organ development; and regulation of gene expression. Predicted to be located in nucleus. Expressed in several structures, including body ganglion; egg-laying apparatus; head neurons; male-specific anatomical entity; and tail ganglion. Human ortholog(s) of this gene implicated in spastic ataxia 8. Is an ortholog of human NKX6-1 (NK6 homeobox 1) and NKX6-2 (NK6 homeobox 2).