gene: nab-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin filament binding activity. Involved in synapse assembly. Located in actin cytoskeleton and presynapse. Expressed in several structures, including egg-laying apparatus; excretory canal; hermaphrodite distal tip cell; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; hepatocellular carcinoma; and schizophrenia. Is an ortholog of human PPP1R9A (protein phosphatase 1 regulatory subunit 9A) and PPP1R9B (protein phosphatase 1 regulatory subunit 9B).
sequence feature: WBsf716914
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=C43E11.6. Surounding gene organisation=divergent