gene: nlg-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable neurexin family protein binding activity and signaling receptor activity. Involved in gamma-aminobutyric acid receptor clustering and negative regulation of neurotransmitter secretion. Located in axon; dendrite; and synapse. Expressed in several structures, including body wall musculature; diagonal muscle; neurons; tail; and ventral nerve cord. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human NLGN4Y (neuroligin 4 Y-linked).