gene: dhfr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable NADP binding activity and dihydrofolate reductase activity. Predicted to be involved in dihydrofolate metabolic process; folic acid metabolic process; and tetrahydrofolate biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Is an ortholog of human DHFR (dihydrofolate reductase); DHFR2 (dihydrofolate reductase 2); and DHFRP1 (dihydrofolate reductase pseudogene 1).