gene: gbf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity. Involved in endosomal transport; organelle organization; and secretion. Located in Golgi cis cisterna and endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate A. Is an ortholog of human GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1).