gene: sod-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables copper ion binding activity; protein homodimerization activity; and superoxide dismutase activity. Involved in regulation of brood size; regulation of vulval development; and removal of superoxide radicals. Located in cytosol and mitochondrion. Expressed in several structures, including intestinal cell; somatic gonad; and somatic nervous system. Used to study amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); eye disease (multiple); and glucose metabolism disease (multiple). Is an ortholog of human SOD1 (superoxide dismutase 1).