gene: pcm-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. Involved in multicellular organismal response to stress; regulation of autophagy; and response to starvation. Located in axon; cytosol; and neuronal cell body. Expressed in several structures, including alimentary muscle; dorso-rectal ganglion; gonad; somatic nervous system; and vulval muscle. Human ortholog(s) of this gene implicated in Alzheimer's disease and malignant astrocytoma. Is an ortholog of human PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase).