gene: let-363 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including box C/D snoRNP assembly; determination of adult lifespan; and regulation of gene expression. Located in cytoplasm. Part of TORC1 complex and TORC2 complex. Expressed in several structures, including intestine; muscle cell; neurons; pharynx; and vulva. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); interstitial cystitis; and kidney angiomyolipoma. Is an ortholog of human MTOR (mechanistic target of rapamycin kinase).