- gene: F27D9.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to be located in membrane. Is an ortholog of human ADAMDEC1 (ADAM like decysin 1).
- strain: GV1
Caenorhabditis elegans - strain: OH1422
Caenorhabditis elegans - strain: AA85
Caenorhabditis elegans - gene: tag-275 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Is an ortholog of human ADAMDEC1 (ADAM like decysin 1).
- gene: adm-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to be located in endosome membrane; lysosomal membrane; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); endocrine gland cancer (multiple); and lung disease (multiple). Is an ortholog of human ADAM19 (ADAM metallopeptidase domain 19) and ADAM33 (ADAM metallopeptidase domain 33).
- gene: adm-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metalloendopeptidase activity. Involved in Notch signaling pathway and cell fate specification. Predicted to be located in plasma membrane. Expressed in gonad; hypodermis; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; inflammatory bowel disease; renal fibrosis; and type 2 diabetes mellitus. Is an ortholog of human ADAM17 (ADAM metallopeptidase domain 17).
- strain: SSM343
Caenorhabditis elegans - gene: unc-71 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Located in membrane. Expressed in several structures, including buccal cavity; excretory system; nerve ring; neuronal sheath cell; and neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 61. Is an ortholog of human ADAM22 (ADAM metallopeptidase domain 22) and ADAM23 (ADAM metallopeptidase domain 23).
- gene: rrc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables GTPase activator activity. Predicted to be involved in signal transduction. Expressed in GLRL; GLRR; coelomocyte; excretory cell; and uterine seam cell. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and coronary artery disease. Is an ortholog of human ARHGAP33 (Rho GTPase activating protein 33).