gene: apx-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable Notch binding activity. Involved in several processes, including lateral inhibition; regulation of germ cell proliferation; and regulation of vulval development. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; non-striated muscle; and vulva. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 1. Is an ortholog of human DLL3 (delta like canonical Notch ligand 3).