Is an ortholog of human SREBF2 (sterol regulatory element binding transcription factor 2). Exhibits DNA-binding transcription factor activity. Is involved in several processes, including determination of adult lifespan; positive regulation of lipid storage; and response to anoxia. Localizes to nucleus. Is expressed in amphid neurons and intestine. Is used to study alcohol use disorder.
Exhibits nuclear hormone receptor binding activity and transcription coactivator activity. Is involved in several processes, including determination of adult lifespan; nematode larval development; and sequestering of triglyceride. Is expressed in head. Is used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene are implicated in syndromic X-linked intellectual disability 34.