gene: mbk-2 [Browse genome (BioProject PRJNA13758)] [Legacy GBrowse]
Is an ortholog of human DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3). Exhibits protein serine/threonine kinase activity and protein tyrosine kinase activity. Is involved in several processes, including P granule disassembly; asymmetric protein localization involved in cell fate determination; and cellular protein modification process. Localizes to several cellular components, including P granule; condensed chromosome; and cytoskeleton. Is expressed in several structures, including body wall musculature; embryonic cell; gonad; oocyte; and pharynx. Is used to study Down syndrome.