gene: lig-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity; DNA binding activity; and DNA ligase (ATP) activity. Involved in DNA repair. Predicted to be located in nucleus. Predicted to be part of DNA ligase IV complex and DNA-dependent protein kinase-DNA ligase 4 complex. Expressed in head neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including DNA ligase IV deficiency; multiple myeloma; and prostate cancer. Is an ortholog of human LIG4 (DNA ligase 4).