gene: dop-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in several processes, including adenylate cyclase-inhibiting dopamine receptor signaling pathway; male mating behavior; and response to odorant. Predicted to be located in postsynaptic membrane and synaptic vesicle membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; end stage renal disease; essential tremor 1; and type 2 diabetes mellitus. Is an ortholog of human DRD3 (dopamine receptor D3).