Phenotypes:

Alleles for which the sequence change is known are listed in boldface.

The following phenotypes have been observed in nca-2:

Phenotype Entities Affected Supporting Evidence
coiling frequency decreasedAllele:
body posture wavelength decreasedAllele:
head bend angle variantAllele:
shortAllele:
amplitude of sinusoidal movement variantAllele:
frequency of body bend variantAllele:
forward locomotion decreasedAllele:
forward point velocity decreasedAllele:
path curvature increasedAllele:
turning frequency variantAllele:
pausing increasedAllele:
body posture amplitude decreasedAllele:
nose movement variantAllele:
tail bend angle variantAllele:
backward point velocity decreasedAllele:
egg size defective early embRNAi:
WBRNAi00041360
Paper evidence: Sonnichsen B et al., 2005
details

Phenotype not observed:
The following phenotypes have been reported as NOT observed in nca-2
Phenotype Entities Affected Supporting Evidence
lethalAllele:
tm8614
Curator: Karen Yook
Person evidence: National Bioresource Project c/o Dr. Shohei Mitani
Remark: Classified as homozygous viable by the National BioResource Project of Japan.
details
lethalAllele:
tm8433
Curator: Karen Yook
Person evidence: National Bioresource Project c/o Dr. Shohei Mitani
Remark: Classified as homozygous viable by the National BioResource Project of Japan.
details
lethalAllele:
tm1305
Curator: Karen Yook
Person evidence: National Bioresource Project c/o Dr. Shohei Mitani
Remark: Classified as homozygous viable by the National Bioresource Project of Japan.
details
lethalAllele:
tm377
Curator: Karen Yook
Person evidence: National Bioresource Project c/o Dr. Shohei Mitani
Remark: Classified as homozygous viable by the National Bioresource Project of Japan.
details
locomotion variantAllele:
gk5
Curator: Karen Yook
Paper evidence: Yeh E et al., 2008
Remark: The single mutant displays normal locomotion.
details
larval lethalRNAi:
WBRNAi00011268
Paper evidence: Kamath RS et al., 2003
details
postembryonic development variantRNAi:
WBRNAi00011268
Paper evidence: Kamath RS et al., 2003
details
maternal sterileRNAi:
WBRNAi00041359
Paper evidence: Sonnichsen B et al., 2005
details
embryonic development variantRNAi:
WBRNAi00005231
Paper evidence: Gonczy P et al., 2000
Remark: DIC phenotype -- Embryonic development normal
details
organism morphology variantRNAi:
WBRNAi00041360
Paper evidence: Sonnichsen B et al., 2005
details
slow growthRNAi:
WBRNAi00013467
Paper evidence: Kamath RS et al., 2003
details
nematode phenotypeRNAi:
WBRNAi00005146
Paper evidence: Gonczy P et al., 2000
details
postembryonic development variantRNAi:
WBRNAi00005088
Paper evidence: Gonczy P et al., 2000
Remark: DIC phenotype -- Embryonic development normal
details
maternal sterileRNAi:
WBRNAi00011268
Paper evidence: Kamath RS et al., 2003
details
nematode phenotypeRNAi:
WBRNAi00011268
Paper evidence: Kamath RS et al., 2003
details
nematode phenotypeRNAi:
WBRNAi00044887
Paper evidence: Sonnichsen B et al., 2005
details
slow growthRNAi:
WBRNAi00011267
Paper evidence: Kamath RS et al., 2003
details
embryonic lethalRNAi:
WBRNAi00011268
Paper evidence: Kamath RS et al., 2003
details
postembryonic development variantRNAi:
WBRNAi00013467
Paper evidence: Kamath RS et al., 2003
details
germline proliferation variantRNAi:
nematode phenotypeRNAi:
WBRNAi00011267
Paper evidence: Kamath RS et al., 2003
details
embryonic lethalRNAi:
WBRNAi00013467
Paper evidence: Kamath RS et al., 2003
details
embryonic development variantRNAi:
WBRNAi00005088
Paper evidence: Gonczy P et al., 2000
Remark: DIC phenotype -- Embryonic development normal
details
organism morphology variantRNAi:
WBRNAi00044887
Paper evidence: Sonnichsen B et al., 2005
details
sterile progenyRNAi:
WBRNAi00011268
Paper evidence: Kamath RS et al., 2003
details
nematode phenotypeRNAi:
WBRNAi00005088
Paper evidence: Gonczy P et al., 2000
details
larval lethalRNAi:
WBRNAi00013467
Paper evidence: Kamath RS et al., 2003
details
maternal sterileRNAi:
WBRNAi00044887
Paper evidence: Sonnichsen B et al., 2005
details
nematode phenotypeRNAi:
WBRNAi00041360
Paper evidence: Sonnichsen B et al., 2005
details
embryonic development variantRNAi:
WBRNAi00005146
Paper evidence: Gonczy P et al., 2000
Remark: DIC phenotype -- Embryonic development normal
details
larval arrestRNAi:
WBRNAi00013467
Paper evidence: Kamath RS et al., 2003
details
embryonic lethalRNAi:
WBRNAi00044887
Paper evidence: Sonnichsen B et al., 2005
details
embryonic lethalRNAi:
WBRNAi00041360
Paper evidence: Sonnichsen B et al., 2005
details
larval arrestRNAi:
WBRNAi00011267
Paper evidence: Kamath RS et al., 2003
details
organism morphology variantRNAi:
WBRNAi00041359
Paper evidence: Sonnichsen B et al., 2005
details
postembryonic development variantRNAi:
WBRNAi00005231
Paper evidence: Gonczy P et al., 2000
Remark: DIC phenotype -- Embryonic development normal
details
embryonic lethalRNAi:
WBRNAi00041359
Paper evidence: Sonnichsen B et al., 2005
details
larval lethalRNAi:
WBRNAi00011267
Paper evidence: Kamath RS et al., 2003
details
postembryonic development variantRNAi:
WBRNAi00011267
Paper evidence: Kamath RS et al., 2003
details
slow growthRNAi:
WBRNAi00011268
Paper evidence: Kamath RS et al., 2003
details
nematode phenotypeRNAi:
WBRNAi00005231
Paper evidence: Gonczy P et al., 2000
details
maternal sterileRNAi:
WBRNAi00011267
Paper evidence: Kamath RS et al., 2003
details
sterile progenyRNAi:
WBRNAi00013467
Paper evidence: Kamath RS et al., 2003
details
nematode phenotypeRNAi:
WBRNAi00013467
Paper evidence: Kamath RS et al., 2003
details
maternal sterileRNAi:
WBRNAi00041360
Paper evidence: Sonnichsen B et al., 2005
details
postembryonic development variantRNAi:
WBRNAi00005146
Paper evidence: Gonczy P et al., 2000
Remark: DIC phenotype -- Embryonic development normal
details
embryonic lethalRNAi:
WBRNAi00011267
Paper evidence: Kamath RS et al., 2003
details
larval arrestRNAi:
WBRNAi00011268
Paper evidence: Kamath RS et al., 2003
details
nematode phenotypeRNAi:
maternal sterileRNAi:
WBRNAi00013467
Paper evidence: Kamath RS et al., 2003
details
sterile progenyRNAi:
WBRNAi00011267
Paper evidence: Kamath RS et al., 2003
details
nematode phenotypeRNAi:
WBRNAi00041359
Paper evidence: Sonnichsen B et al., 2005
details

Interaction-based phenotypes:

The following phenotypes are indirectly caused or affected by some perturbation of nca-2 in the context of a genetic interaction :

Phenotype Interactions Interaction Type Citations
evoked postsynaptic current variant21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77SyntheticYeh E et al., 2008
evoked postsynaptic current variant21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77A phenotypicYeh E et al., 2008
evoked postsynaptic current variant21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77DivergingYeh E et al., 2008
fainter21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77SyntheticYeh E et al., 2008
fainter21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77A phenotypicYeh E et al., 2008
fainter21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77DivergingYeh E et al., 2008
endogenous synaptic event frequency reduced21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77SyntheticYeh E et al., 2008
endogenous synaptic event frequency reduced21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77A phenotypicYeh E et al., 2008
endogenous synaptic event frequency reduced21ur-14100 : 21ur-2262 : 21ur-4260 : 21ur-4646 : 21ur-5158 : 21ur-7268 : 21ur-8078 : nca-2 : unc-77DivergingYeh E et al., 2008

Overexpression:
Overexpression of the nca-2 gene results in the following phenotypes.