Consistent with a role in docking and fusion of vesicles, loss of rab-10 and exoc-8 caused severe accumulation of DMA-1::GFP containing vesicles within the growing PVD dendrites.
"ZNFX-1 (ZK1067.2) binds RdRP (EGO-1) and the Argonautes CSR-1, PRG-1, and WAGO-1."; "the ZNFX-1 interactions with WAGO-1 and PRG-1 were partially sensitive to RNase I."
"ZNFX-1 (ZK1067.2) binds RdRP (EGO-1) and the Argonautes CSR-1, PRG-1, and WAGO-1."; "the ZNFX-1 interactions with WAGO-1 and PRG-1 were partially sensitive to RNase I."
"Knockdown of these genes [fars-1, hars-1, lars-1, nars-1, rrt-1, sars-1] also significantly (P < 0.01) increased mRNA levels for gpdh-1 ~ 1.7- to nearly 40-fold (Fig. 1, C and D)."