smf-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable cadmium ion transmembrane transporter activity; iron ion transmembrane transporter activity; and manganese ion transmembrane transporter activity. Involved in several processes, including defense response to Gram-negative bacterium; monoatomic cation homeostasis; and response to manganese ion. Located in apical plasma membrane and organelle membrane. Expressed in several structures, including excretory cell; hypodermal cell; intestinal cell; neurons; and vulva. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); leishmaniasis (multiple); and neurodegenerative disease (multiple). Is an ortholog of human SLC11A1 (solute carrier family 11 member 1) and SLC11A2 (solute carrier family 11 member 2).