tor-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in cellular response to misfolded protein; negative regulation of gene expression; and regulation of neuron apoptotic process. Located in endoplasmic reticulum. Expressed in neurons. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-5 and torsion dystonia 1. Is an ortholog of human TOR1A (torsin family 1 member A) and TOR1B (torsin family 1 member B).