ife-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA 7-methylguanosine cap binding activity and RNA trimethylguanosine cap binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of response to oxidative stress; and positive regulation of translation. Located in cytoplasmic stress granule. Expressed in several structures, including excretory canal; germ line; pharynx; spermatheca; and vulva. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human EIF4E (eukaryotic translation initiation factor 4E) and EIF4E1B (eukaryotic translation initiation factor 4E family member 1B).