dsh-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables receptor tyrosine kinase binding activity. Involved in Wnt signaling pathway, regulating spindle positioning. Predicted to be located in cytosol. Expressed in several structures, including germ line; gonad; neurons; tail; and vulva. Human ortholog(s) of this gene implicated in DiGeorge syndrome and autosomal dominant Robinow syndrome 2. Is an ortholog of human DVL1 (dishevelled segment polarity protein 1).