ceh-34 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables sequence-specific DNA binding activity. Involved in mesodermal cell fate specification; positive regulation of apoptotic process involved in development; and regulation of DNA-templated transcription. Located in nucleus. Expressed in body wall musculature; corpus; head; male sex myoblast; and pharyngeal neurons. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant nonsyndromic deafness 23; carcinoma (multiple); and renal Wilms' tumor. Is an ortholog of human SIX1 (SIX homeobox 1) and SIX2 (SIX homeobox 2).