gene: hda-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable histone deacetylase activity and transcription corepressor activity. Involved in DNA protection. Located in nucleus. Expressed in several structures, including ASHL and ASHR. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); and prostate disease (multiple). Is an ortholog of human HDAC1 (histone deacetylase 1) and HDAC2 (histone deacetylase 2).