- gene: unc-70 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin filament binding activity. Involved in several processes, including dendrite development; embryonic body morphogenesis; and muscle cell cellular homeostasis. Located in cell junction; contractile fiber; and lateral plasma membrane. Expressed in hermaphrodite gonad and vulval cell. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 14; hereditary spherocytosis type 2; and spinocerebellar ataxia type 5. Is an ortholog of human SPTB (spectrin beta, erythrocytic).
- sequence feature: WBsf716817
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=K11C4.3. Surounding gene organisation=tandem
- sequence feature: WBsf717234
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=K11C4.3. Surounding gene organisation=tandem
- sequence feature: WBsf717233
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=K11C4.3. Surounding gene organisation=tandem
- sequence feature: WBsf718331
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=K11C4.3. Surounding gene organisation=tandem