gene: nlr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables actin filament binding activity and gap junction channel activity. Involved in positive regulation of gap junction assembly and positive regulation of pharyngeal pumping. Located in gap junction. Expressed in RIS; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Pitt-Hopkins syndrome; autistic disorder; and communication disorder (multiple). Is an ortholog of human CNTNAP5 (contactin associated protein family member 5).