gene: mdf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein kinase binding activity. Involved in embryo development; mitotic spindle assembly; and regulation of mitotic sister chromatid separation. Located in kinetochore; nuclear membrane; and nuclear periphery. Expressed in Z1; Z2; Z3; Z4; and intestine. Human ortholog(s) of this gene implicated in lymphoma; mosaic variegated aneuploidy syndrome; and prostate cancer. Is an ortholog of human MAD1L1 (mitotic arrest deficient 1 like 1).