Enriched in several structures, including body wall muscle cell; head mesodermal cell; intestinal muscle; neurons; and rectal muscle based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including
daf-16;
daf-2; and
skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. Human MTCL1 enables microtubule binding activity. Is an ortholog of human MTCL1 (microtubule crosslinking factor 1) and MTCL2 (microtubule crosslinking factor 2).