gene: dsh-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable frizzled binding activity. Involved in several processes, including Wnt signaling pathway, regulating spindle positioning; embryonic morphogenesis; and left/right axis specification. Located in cell cortex. Expressed in several structures, including QL; QR; distal tip cell; midbody; and somatic gonad precursor. Human ortholog(s) of this gene implicated in DiGeorge syndrome; Robinow syndrome (multiple); and lung cancer. Is an ortholog of human DVL1 (dishevelled segment polarity protein 1).