gene: ccm-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein kinase binding activity. Involved in several processes, including endoplasmic reticulum organization; positive regulation of endocytic recycling; and regulation of Golgi organization. Located in cytoplasm; cytoplasmic side of apical plasma membrane; and growing cell tip. Expressed in several structures, including excretory canal; germ line; intestinal cell; oocyte; and pharynx. Used to study cerebral cavernous malformation. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 3. Is an ortholog of human PDCD10 (programmed cell death 10).